2024

Thakkar, K.N., Silverstein, S.M., Fattal, J., Bao, J., Slate, R., Roberts, D., Brascamp, J.W. (2024). Stronger tilt aftereffects in individuals diagnosed with schizophrenia spectrum disorders but not bipolar disorder. Schizophrenia 264, 345–353. PDF 

Yao, B., Rolfs, M., Slate, R., Roberts, D., Fattal, J. Achtyes, E.D., Tso, I.F., Diwadkar, V.A., Kashy, D., Bao, J., Thakkar, K.N. (2024) Abnormal oculomotor corollary discharge signaling as a trans-diagnostic mechanism of psychosis. Schizophrenia Bulletin 50(3), 631–641. PDF

Lehet, M., Rolfs, M., Bao, J., Fattal, J., Thakkar, K.N. (2024) Pre‐saccadic shifts of attention in individuals diagnosed with schizophrenia. Brain and Behavior 14(3), e3466. PDF

2023

Roberts, D., Rösler, L., Wijnen, J., Thakkar, K.N. (2023) Associations between N-Acetylaspartate and white matter integrity in individuals with schizophrenia and unaffected relatives. Psychiatry Research: Neuroimaging, 330: 111612. PDF

Thakkar, K.N., McCleery, A., Minor, K.S., Lee, J., Humpston, C.S. Chopik, W.J., Burt, S.A., Pearson, A.L., Ungar, M., Park, S. (2023) Moving from risk to resilience in psychosis research, Nature Reviews Psychology. PDF

Hasan, S.M., Huq, M.S., Chowdury, A.Z., Baajour, S., Kopchick, J., Robison, A.J., Thakkar, K.N., Haddad, L., Amirsadri, A., Thomas, P., Khatib, D., Rajan, U., Stanley, J.A., Diwadkar, V.A. (2023). Learning without contingencies: A loss of synergy between memory and reward circuits in schizophrenia. Schizophrenia Research 258, 21-35. PDF

Merritt, K., Aleman, A., Block, W., [et al, including Thakkar, K.N.] (2023) Variability and Magnitude of Brain Glutamate Levels in Schizophrenia: A Meta And Mega-Analysis. Molecular Psychiatry. PDF

Yao, B., Gu, P., Lasagna, C. A., Peltier, S., Taylor, S. F., Tso, I. F., & Thakkar, K. N. (2023). Structural connectivity of an interoception network in schizophrenia. Psychiatry Research: Neuroimaging, 331: 111636. PDF

2022

Fry BR, Roberts D, Thakkar KN, Johnson AW. (2022). Variables influencing conditioning-evoked hallucinations: overview and future applications. Psychol Med, 1-13. PDF

Culbert, K., Thakkar, K.N., Klump, K. (2022). Risk for midlife psychosis in women: Critical gaps and opportunities in exploring perimenopause and ovarian hormones as mechanisms of risk. Psychological Medicine, 1-9. PDF

Fattal J., Brascamp J.W., Slate R., Lehet, M., Achtyes, E., Thakkar, K.N. (2022) Blunted pupil light reflex is associated with negative symptoms and working memory in individuals with schizophrenia. Schizophrenia Research 248, 254–262. PDF

Migó M., Guillory S.B., McLaughlin C.S., Isenstein E.L., Grosman H.E., Thakkar K.N., Castellanos F.X., Foss-Feig J.H. (2022) Investigating Motor Preparation in Autism Spectrum Disorder With and Without Attention Deficit/Hyperactivity Disorder. Journal of Autism and Developmental Disorders 52, 2379–2387. PDF

Yao, B., Thakkar, K.N. (2022) Interoception abnormalities in schizophrenia: A review of preliminary evidence and an integration with Bayesian accounts of psychosis. Neuroscience and Biobehavioral Reviews 132, 757-773. PDF

2021

Barr, S.M., Roberts, D., Thakkar, K.N. (2021) Psychosis in transgender and gender non-conforming individuals: A review of the literature and a call for more research. Psychiatry Research 306: 114272. PDF

Lehet, M., Tso, I.F., Park, S., Neggers, S.F.W., Thompson, I.A., Kahn, R.S., Thakkar, K.N. (2021) Altered Effective Connectivity within an Oculomotor Control Network in Unaffected Relatives of Individuals with Schizophrenia. Brain Sciences 11(9), 1228. PDF

Yao, B., Rolfs, M., McLaughlin, C., Isenstein, E.L., Guillory, S.B., Grosman, H., Kashy, D.A., Foss-Feig, J.H., Thakkar, K.N. (2021) Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder. Journal of Vision 21(9), 1-20. PDF

Lehet, M., Tso, I.F., Neggers, S.F.W., Thompson, I.A., Yao, B., Kahn, R.S., Thakkar, K.N. (2021) Altered effective connectivity within an oculomotor control network in individuals with schizophrenia. NeuroImage: Clinical 31, 2213-1582. PDF

Dave, A., Lehet, M., Diwadkar, V.A., Thakkar, K.N. (2021) Ocular measures during associative learning predict recall accuracy. International Journal of Psychophysiology 166, 103-115. PDF

Merritt K., McGuire P.K., Egerton A., [et al, including Thakkar, K.N.] (2021) Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data. JAMA Psychiatry 78(6), 667–681. PDF

Chopik, W. J., Oh, J., Nuttall, A. K., Thakkar, K. N., Ingersoll, B. (2021) Age differences in Broader Autism Phenotype traits from young adulthood to older adulthood. Autism Research. PDF

Thakkar, K.N., Mathalon, D.H., Ford, J.M. (2021) Reconciling competing mechanisms posited to underlie auditory verbal hallucinations. Philosophical Transactions of the Royal Society B: Biological Sciences 376, 20190702PDF

Thakkar, K.N., Ghermezi, L., Slate, R., Silverstein, S.M., Achtyes, E.A., Brascamp, J.W., Yao, B. (2021) Stronger tilt aftereffects in persons with schizophrenia. Journal of Abnormal Psychology 130(2), 186-197.  PDF

2020

Yao, B., Neggers, S.F.W., Kahn, R.S., Thakkar, K.N. (2020) Altered thalamocortical structural connectivity in persons with schizophrenia and unaffected siblings. Neuroimage: Clinical, 28: 102370. PDF

Tso, I.F., Lasagna, C.A., Fitzgerald, K.D., Colombi, C. Sripada, C.S., Peltier, S., Johnson, T.D., Thakkar, K.N. (2020) Disrupted eye gaze perception as a biobehavioral marker of social dysfunction: An RDoC investigation. Journal of Psychiatry and Brain Science, 5: e200021. PDF

Robison, A.J., Thakkar, K.N., Diwadkar, V. (2020) Cognition and reward circuits in schizophrenia: synergistic, not separate. Biological Psychiatry, 87, 204-214 PDF 

2019

Thakkar, K.N., Antinori, A., Carter, O., Brascamp, J.W. (2019) Altered short-term synaptic plasticity related to schizotypal traits: evidence from visual adaptation. Schizophrenia Research. PDF

Thakkar, K.N., Rolfs, M. (2019) Disrupted corollary discharge in schizophrenia: evidence from the oculomotor system. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 773-781. PDF

Thakkar, K.N., Silverstein, S.M., Brascamp, J.W. (2019) A review of visual aftereffects in schizophrenia. Neuroscience and Biobehavioral Reviews, 101: 68-77. PDF

Yao, B., Neggers, S.F.W., Rolfs, M., Rösler, L., Thompson, I.A., Hopman, H.J., Ghermezi, L., Kahn, R.S., Thakkar, K.N. (2019) Structural thalamo-frontal hypoconnectivity is related to oculomotor corollary discharge in schizophrenia. Journal of Neuroscience, 39: 2102: 2113. PDF

Nuttall, A.K., Thakkar, K.N., Luo, X., Mueser, K.T., Glynn, S.M., Achtyes, E.D., Kane, J.M. (2019) Longitudinal associations of family burden and patient quality of life in the context of first-episode schizophrenia in the RAISE-ETP study. Psychiatry Research, 276: 60-68. PDF

Verbruggen, F., Aron, A. R., Band, G., [et al, including Thakkar, K.N.] (2019) Capturing the ability to inhibit actions and impulsive behaviors: A consensus guide to the stop-signal task. eLife;8:e46323. PDF

2018

Thakkar, K.N., Brascamp, J.W., Ghermezi, L., Fifer, K., Schall, J.D., Park, S. (2018) Reduced pupil diation during action preparation in schizophrenia. International Journal of Psychophysiology. PDF

Yao, B., Mueller, S., Grove, T., McLaughlin, M., Thakkar, K.N., Ringold, V., McInnis, M., Taylor, S., Deldin, P., Tso, I. (2018) Eye Gaze Perception in Bipolar Disorder: Self-referential Bias but Intact Perceptual Sensitivity. Bipolar Disorders, 20: 60-69. PDF

2017

Thakkar, K.N., Diwadkar, V., Rolfs, M. (2017) Oculomotor prediction: a window into the psychotic mind. Trends in Cognitive Sciences, 21:344-356. PDF

Thakkar, K.N., Rösler, L., Wijnen, J.P., Boer, V.O., Klomp, D.W.J., Cahn, W., Kahn, R.S., Neggers, S.F.W. (2017) 7T proton magnetic resonance spectroscopy of GABA, glutamate, and glutamine in schizophrenia reveals altered metabolite concentrations in patients and unaffected relatives. Biological Psychiatry, 81:525-535.  PDF

2016

Zerr, P., Thakkar, K.N., Uzunbajakau, S., Van der Stigchel, S. (2016) Error compensation in random vector double step saccades with and without global adaptation. Vision Research, 127:141-151. PDF

Thakkar, K.N, van den Heiligenberg, F.M.Z., Kahn, R.S., Neggers, S.F.W. (2016) Cortico-striatal white matter structure predicts latencies of saccade execution and redirection. Human Brain Mapping, 37: 2811-2822.  PDF

Asscheman, S.J., Thakkar, K.N., Neggers, S.F.W. (2016) Changes in effective connectivity of the superior parietal lobe during inhibition and redirection of eye movements. Journal of Experimental Neuroscience, 9(Suppl 1): 27-40.  PDF

2015

Thakkar, K.N., Schall, J.D., Heckers, S., Park, S. (2015) Disrupted saccadic corollary discharge in schizophrenia. Journal of Neuroscience, 35(27): 9935-9945. PDF

Rösler, L., Rolfs, M., van der Stigchel, S., Neggers, S.F.W., Cahn, W., Kahn, R.S, Thakkar, K.N. (2015) Failure to use corollary discharge to remap visual target locations is associated with psychotic symptom severity in schizophrenia. Journal of Neurophysiology, 114: 129-1136. PDF

Thakkar, K.N., Schall, J.D., Logan, G.D., Park, S. (2015) Response inhibition and response monitoring in a saccadic double-step task in schizophrenia. Brain and Cognition, 95: 90-98. PDF

Thakkar, K.N., Schall, J.D., Logan, G.D., Park, S. (2015) Cognitive control of gaze in bipolar disorder and schizophrenia. Psychiatry Research, 225: 254-262. PDF

2014

Thakkar, K.N., van den Heiligenberg, F. Kahn, R.S., Neggers, S.F.W. (2014) Fronto-striatal contributions to reactive control of gaze. Journal of Neuroscience, 34(26): 8918-8929. PDF

Thakkar, K.N., Peterman, J.S., Park, S. (2014) Altered brain activation during action imitation and observation in schizophrenia: a translational approach for studying social dysfunction. American Journal of Psychiatry, 171(5): 539-548. PDF

Thakkar, K.N., Congdon, E., Poldrack, R.A., Sabb, F.W., London, E.D., Cannon, T.D., Bilder, R.M. (2014) Women are more sensitive than men to prior trial events on the stop signal task. British Journal of Psychology, 105(2):254-72. PDF

Matthews, N., Collins, K., Thakkar, K.N., Park, S. (2014) Visuospatial imagery and working memory in schizophrenia. Cognitive Neuropsychiatry, 19(1): 17-35. PDF

2012

Thakkar, K.N., Park, S. (2012) Impaired passive maintenance and spared manipulation of internal representations in patients with schizophrenia. Schizophrenia Bulletin, 38(4): 787-795. PDF

2011

Thakkar, K.N., Nichols, H.S., McIntosh, L.G., Park, S. (2011) Disturbances in body ownership in patients with schizophrenia: evidence from the rubber hand illusion and case study of a spontaneous out-of-body experience. PLoS ONE, 6(10): e27089. PDF

Roffman, J.L., Brohawn, D.G., Friedman, J.S., Dyckman, K.A., Thakkar, K.N., Agam, Y., Vangel, M.G., Goff, D.C., Manoach, D.S. (2011) MTHFR 677C>T effects on anterior cingulate structure and function during response monitoring in schizophrenia: a preliminary study. Brain Imaging and Behavior, 5(1): 65-75. PDF

Thakkar, K.N., Schall, J.D., Boucher, L., Logan, G.D., Park, S. (2011) Response inhibition and response monitoring in a saccadic countermanding task in schizophrenia. Biological Psychiatry, 69: 55-62. PDF

2010

Thakkar, K.N., & Park, S. (2010) Empathy, schizotypy, and spatial transformations. Cognitive Neuropsychiatry, 15: 477-500. PDF

Manoach, D.S., Thakkar, K.N., Stroynowski, E., Ely, A., McKinley, S.K., Djonlagic, I., Vangel,M.G., Goff, D.C., Stickgold, R.S. (2010). Reduced overnight consolidation of procedural learning in chronic medicated schizophrenia is related to specific sleep stages. Journal of Psychiatric Research, 44: 112-120. PDF

Commentary
Park, S. & Thakkar, K.N. (2010) “Splitting of the mind” revisited: recent neuroimaging evidence for functional dysconnection in schizophrenia. American Journal of Psychiatry, 167: 366-368. PDF

2009

Thakkar, K.N., Brugger, P., Park, S. (2009). Exploring empathic space: correlates of perspective transformation ability and biases in spatial attention. PLoS ONE, 4(6): e5864. PDF

2008

Thakkar, K.N., Polli, F.E., Joseph, R.M., Tuch, D.S., Hadjikhani, N., Barton, J.J.S., Manoach, D.S. (2008). Abnormal response monitoring, repetitive behavior, and decreased microstructural integrity of white matter underlying anterior cingulate cortex in autism spectrum disorders. Brain, 131: 2464-78. PDF

Polli, F.E., Barton, J.J.S., Thakkar, K.N., Cain, M.S., Goff, D.C., Rauch, S.L., Manoach, D.S. (2008) Reduced error-related activation in two anterior cingulate circuits is related toimpaired performance in schizophrenia. Brain, 131(4): 971-86. PDF

Barton, J.J.S., Pandita, M.,Thakkar, K.N., Goff, D.C., Manoach, D.S. (2008) The relation between antisaccade errors, fixation stability and prosaccade errors in schizophrenia. Experimental Brain Research, 186(2):273-82. PDF

Commentary
Thakkar, K.N., Matthews, N., Park, S. (2008) A complete theory of psychosis and autism as diametric disorders of the social brain must consider full range of clinical syndromes. Behavioral and Brain Sciences, 31(3): 277-278. PDF

2007 and earlier

Manoach, D.S., Ketwaroo, G.A., Polli, F.E., Thakkar, K.N., Barton, J.J.S., Goff, D.C., Vangel, M., Tuch, D.S. (2007). The association of reduced microstructural integrity of the anterior cingulum bundle is associated with increased saccadic latency in schizophrenia. Neuroimage, 37(2):599-610. PDF

Manoach, D.S., Thakkar, K.N., Cain, M.S., Polli, F.E., Edelman, J., Barton, J.J.S. (2007). Neural activity is modulated by trial history: An fMRI study of the effects of a prior antisaccade. Journal of Neuroscience, 27(7): 1791-1798. PDF

Polli, F.E., Barton, J.J.S., Cain, M.S., Thakkar, K.N. Rauch, S.L., Manoach, D.S (2005). Rostral and dorsal anterior cingulate cortex make dissociable contributions during antisaccade error commission. Proceedings of the National Academy of Sciences, 102(43): 15700-5. PDF

In Press

Lehet, M., Rolfs, M., Bao, J., Fattal, J., Thakkar, K.N. (in press) Pre‐saccadic shifts of attention in individuals diagnosed with schizophrenia. PDF
 

Yao, B., Rolfs, M., Slate, R., Roberts, D., Fattal, J. Achtyes, E.D., Tso, I.F., Diwadkar, V.A., Kashy, D., Bao, J., Thakkar, K.N. (in press) Abnormal oculomotor corollary discharge signaling as a trans-diagnostic mechanism of psychosis. Schizophrenia Bulletin. PDF

Thakkar, K.N., Silverstein, S.M., Fattal, J., Bao, J., Slate, R., Roberts, D., Brascamp, J.W. (in press). Stronger tilt aftereffects in individuals diagnosed with schizophrenia spectrum disorders but not bipolar disorder. Schizophrenia Research. PDF

2024

 

2023

Roberts, D., Rösler, L., Wijnen, J., Thakkar, K.N. (2023) Associations between N-Acetylaspartate and white matter integrity in individuals with schizophrenia and unaffected relatives. Psychiatry Research: Neuroimaging, 330: 111612. PDF

Thakkar, K.N., McCleery, A., Minor, K.S., Lee, J., Humpston, C.S. Chopik, W.J., Burt, S.A., Pearson, A.L., Ungar, M., Park, S. (2023) Moving from risk to resilience in psychosis research, Nature Reviews Psychology. PDF

Hasan, S.M., Huq, M.S., Chowdury, A.Z., Baajour, S., Kopchick, J., Robison, A.J., Thakkar, K.N., Haddad, L., Amirsadri, A., Thomas, P., Khatib, D., Rajan, U., Stanley, J.A., Diwadkar, V.A. (2023). Learning without contingencies: A loss of synergy between memory and reward circuits in schizophrenia. Schizophrenia Research 258, 21-35. PDF

Merritt, K., Aleman, A., Block, W., [et al, including Thakkar, K.N.] (2023) Variability and Magnitude of Brain Glutamate Levels in Schizophrenia: A Meta And Mega-Analysis. Molecular Psychiatry. PDF

Yao, B., Gu, P., Lasagna, C. A., Peltier, S., Taylor, S. F., Tso, I. F., & Thakkar, K. N. (2023). Structural connectivity of an interoception network in schizophrenia. Psychiatry Research: Neuroimaging, 331: 111636. PDF

2022

Fry BR, Roberts D, Thakkar KN, Johnson AW. (2022). Variables influencing conditioning-evoked hallucinations: overview and future applications. Psychol Med, 1-13. PDF

Culbert, K., Thakkar, K.N., Klump, K. (2022). Risk for midlife psychosis in women: Critical gaps and opportunities in exploring perimenopause and ovarian hormones as mechanisms of risk. Psychological Medicine, 1-9. PDF

Fattal J., Brascamp J.W., Slate R., Lehet, M., Achtyes, E., Thakkar, K.N. (2022) Blunted pupil light reflex is associated with negative symptoms and working memory in individuals with schizophrenia. Schizophrenia Research 248, 254–262. PDF

Migó M., Guillory S.B., McLaughlin C.S., Isenstein E.L., Grosman H.E., Thakkar K.N., Castellanos F.X., Foss-Feig J.H. (2022) Investigating Motor Preparation in Autism Spectrum Disorder With and Without Attention Deficit/Hyperactivity Disorder. Journal of Autism and Developmental Disorders 52, 2379–2387. PDF

Yao, B., Thakkar, K.N. (2022) Interoception abnormalities in schizophrenia: A review of preliminary evidence and an integration with Bayesian accounts of psychosis. Neuroscience and Biobehavioral Reviews 132, 757-773. PDF

2021

Barr, S.M., Roberts, D., Thakkar, K.N. (2021) Psychosis in transgender and gender non-conforming individuals: A review of the literature and a call for more research. Psychiatry Research 306: 114272. PDF

Lehet, M., Tso, I.F., Park, S., Neggers, S.F.W., Thompson, I.A., Kahn, R.S., Thakkar, K.N. (2021) Altered Effective Connectivity within an Oculomotor Control Network in Unaffected Relatives of Individuals with Schizophrenia. Brain Sciences 11(9), 1228. PDF

Yao, B., Rolfs, M., McLaughlin, C., Isenstein, E.L., Guillory, S.B., Grosman, H., Kashy, D.A., Foss-Feig, J.H., Thakkar, K.N. (2021) Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder. Journal of Vision 21(9), 1-20. PDF

Lehet, M., Tso, I.F., Neggers, S.F.W., Thompson, I.A., Yao, B., Kahn, R.S., Thakkar, K.N. (2021) Altered effective connectivity within an oculomotor control network in individuals with schizophrenia. NeuroImage: Clinical 31, 2213-1582. PDF

Dave, A., Lehet, M., Diwadkar, V.A., Thakkar, K.N. (2021) Ocular measures during associative learning predict recall accuracy. International Journal of Psychophysiology 166, 103-115. PDF

Merritt K., McGuire P.K., Egerton A., [et al, including Thakkar, K.N.] (2021) Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data. JAMA Psychiatry 78(6), 667–681. PDF

Chopik, W. J., Oh, J., Nuttall, A. K., Thakkar, K. N., Ingersoll, B. (2021) Age differences in Broader Autism Phenotype traits from young adulthood to older adulthood. Autism Research. PDF

Thakkar, K.N., Mathalon, D.H., Ford, J.M. (2021) Reconciling competing mechanisms posited to underlie auditory verbal hallucinations. Philosophical Transactions of the Royal Society B: Biological Sciences 376, 20190702PDF

Thakkar, K.N., Ghermezi, L., Slate, R., Silverstein, S.M., Achtyes, E.A., Brascamp, J.W., Yao, B. (2021) Stronger tilt aftereffects in persons with schizophrenia. Journal of Abnormal Psychology 130(2), 186-197.  PDF

2020

Yao, B., Neggers, S.F.W., Kahn, R.S., Thakkar, K.N. (2020) Altered thalamocortical structural connectivity in persons with schizophrenia and unaffected siblings. Neuroimage: Clinical, 28: 102370. PDF

Tso, I.F., Lasagna, C.A., Fitzgerald, K.D., Colombi, C. Sripada, C.S., Peltier, S., Johnson, T.D., Thakkar, K.N. (2020) Disrupted eye gaze perception as a biobehavioral marker of social dysfunction: An RDoC investigation. Journal of Psychiatry and Brain Science, 5: e200021. PDF

Robison, A.J., Thakkar, K.N., Diwadkar, V. (2020) Cognition and reward circuits in schizophrenia: synergistic, not separate. Biological Psychiatry, 87, 204-214 PDF 

2019

Thakkar, K.N., Antinori, A., Carter, O., Brascamp, J.W. (2019) Altered short-term synaptic plasticity related to schizotypal traits: evidence from visual adaptation. Schizophrenia Research. PDF

Thakkar, K.N., Rolfs, M. (2019) Disrupted corollary discharge in schizophrenia: evidence from the oculomotor system. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 773-781. PDF

Thakkar, K.N., Silverstein, S.M., Brascamp, J.W. (2019) A review of visual aftereffects in schizophrenia. Neuroscience and Biobehavioral Reviews, 101: 68-77. PDF

Yao, B., Neggers, S.F.W., Rolfs, M., Rösler, L., Thompson, I.A., Hopman, H.J., Ghermezi, L., Kahn, R.S., Thakkar, K.N. (2019) Structural thalamo-frontal hypoconnectivity is related to oculomotor corollary discharge in schizophrenia. Journal of Neuroscience, 39: 2102: 2113. PDF

Nuttall, A.K., Thakkar, K.N., Luo, X., Mueser, K.T., Glynn, S.M., Achtyes, E.D., Kane, J.M. (2019) Longitudinal associations of family burden and patient quality of life in the context of first-episode schizophrenia in the RAISE-ETP study. Psychiatry Research, 276: 60-68. PDF

Verbruggen, F., Aron, A. R., Band, G., [et al, including Thakkar, K.N.] (2019) Capturing the ability to inhibit actions and impulsive behaviors: A consensus guide to the stop-signal task. eLife;8:e46323. PDF

2018

Thakkar, K.N., Brascamp, J.W., Ghermezi, L., Fifer, K., Schall, J.D., Park, S. (2018) Reduced pupil diation during action preparation in schizophrenia. International Journal of Psychophysiology. PDF

Yao, B., Mueller, S., Grove, T., McLaughlin, M., Thakkar, K.N., Ringold, V., McInnis, M., Taylor, S., Deldin, P., Tso, I. (2018) Eye Gaze Perception in Bipolar Disorder: Self-referential Bias but Intact Perceptual Sensitivity. Bipolar Disorders, 20: 60-69. PDF

2017

Thakkar, K.N., Diwadkar, V., Rolfs, M. (2017) Oculomotor prediction: a window into the psychotic mind. Trends in Cognitive Sciences, 21:344-356. PDF

Thakkar, K.N., Rösler, L., Wijnen, J.P., Boer, V.O., Klomp, D.W.J., Cahn, W., Kahn, R.S., Neggers, S.F.W. (2017) 7T proton magnetic resonance spectroscopy of GABA, glutamate, and glutamine in schizophrenia reveals altered metabolite concentrations in patients and unaffected relatives. Biological Psychiatry, 81:525-535.  PDF

2016

Zerr, P., Thakkar, K.N., Uzunbajakau, S., Van der Stigchel, S. (2016) Error compensation in random vector double step saccades with and without global adaptation. Vision Research, 127:141-151. PDF

Thakkar, K.N, van den Heiligenberg, F.M.Z., Kahn, R.S., Neggers, S.F.W. (2016) Cortico-striatal white matter structure predicts latencies of saccade execution and redirection. Human Brain Mapping, 37: 2811-2822.  PDF

Asscheman, S.J., Thakkar, K.N., Neggers, S.F.W. (2016) Changes in effective connectivity of the superior parietal lobe during inhibition and redirection of eye movements. Journal of Experimental Neuroscience, 9(Suppl 1): 27-40.  PDF

2015

Thakkar, K.N., Schall, J.D., Heckers, S., Park, S. (2015) Disrupted saccadic corollary discharge in schizophrenia. Journal of Neuroscience, 35(27): 9935-9945. PDF

Rösler, L., Rolfs, M., van der Stigchel, S., Neggers, S.F.W., Cahn, W., Kahn, R.S, Thakkar, K.N. (2015) Failure to use corollary discharge to remap visual target locations is associated with psychotic symptom severity in schizophrenia. Journal of Neurophysiology, 114: 129-1136. PDF

Thakkar, K.N., Schall, J.D., Logan, G.D., Park, S. (2015) Response inhibition and response monitoring in a saccadic double-step task in schizophrenia. Brain and Cognition, 95: 90-98. PDF

Thakkar, K.N., Schall, J.D., Logan, G.D., Park, S. (2015) Cognitive control of gaze in bipolar disorder and schizophrenia. Psychiatry Research, 225: 254-262. PDF

2014

Thakkar, K.N., van den Heiligenberg, F. Kahn, R.S., Neggers, S.F.W. (2014) Fronto-striatal contributions to reactive control of gaze. Journal of Neuroscience, 34(26): 8918-8929. PDF

Thakkar, K.N., Peterman, J.S., Park, S. (2014) Altered brain activation during action imitation and observation in schizophrenia: a translational approach for studying social dysfunction. American Journal of Psychiatry, 171(5): 539-548. PDF

Thakkar, K.N., Congdon, E., Poldrack, R.A., Sabb, F.W., London, E.D., Cannon, T.D., Bilder, R.M. (2014) Women are more sensitive than men to prior trial events on the stop signal task. British Journal of Psychology, 105(2):254-72. PDF

Matthews, N., Collins, K., Thakkar, K.N., Park, S. (2014) Visuospatial imagery and working memory in schizophrenia. Cognitive Neuropsychiatry, 19(1): 17-35. PDF

2012

Thakkar, K.N., Park, S. (2012) Impaired passive maintenance and spared manipulation of internal representations in patients with schizophrenia. Schizophrenia Bulletin, 38(4): 787-795. PDF

2011

Thakkar, K.N., Nichols, H.S., McIntosh, L.G., Park, S. (2011) Disturbances in body ownership in patients with schizophrenia: evidence from the rubber hand illusion and case study of a spontaneous out-of-body experience. PLoS ONE, 6(10): e27089. PDF

Roffman, J.L., Brohawn, D.G., Friedman, J.S., Dyckman, K.A., Thakkar, K.N., Agam, Y., Vangel, M.G., Goff, D.C., Manoach, D.S. (2011) MTHFR 677C>T effects on anterior cingulate structure and function during response monitoring in schizophrenia: a preliminary study. Brain Imaging and Behavior, 5(1): 65-75. PDF

Thakkar, K.N., Schall, J.D., Boucher, L., Logan, G.D., Park, S. (2011) Response inhibition and response monitoring in a saccadic countermanding task in schizophrenia. Biological Psychiatry, 69: 55-62. PDF

2010

Thakkar, K.N., & Park, S. (2010) Empathy, schizotypy, and spatial transformations. Cognitive Neuropsychiatry, 15: 477-500. PDF

Manoach, D.S., Thakkar, K.N., Stroynowski, E., Ely, A., McKinley, S.K., Djonlagic, I., Vangel,M.G., Goff, D.C., Stickgold, R.S. (2010). Reduced overnight consolidation of procedural learning in chronic medicated schizophrenia is related to specific sleep stages. Journal of Psychiatric Research, 44: 112-120. PDF

Commentary
Park, S. & Thakkar, K.N. (2010) “Splitting of the mind” revisited: recent neuroimaging evidence for functional dysconnection in schizophrenia. American Journal of Psychiatry, 167: 366-368. PDF

2009

Thakkar, K.N., Brugger, P., Park, S. (2009). Exploring empathic space: correlates of perspective transformation ability and biases in spatial attention. PLoS ONE, 4(6): e5864. PDF

2008

Thakkar, K.N., Polli, F.E., Joseph, R.M., Tuch, D.S., Hadjikhani, N., Barton, J.J.S., Manoach, D.S. (2008). Abnormal response monitoring, repetitive behavior, and decreased microstructural integrity of white matter underlying anterior cingulate cortex in autism spectrum disorders. Brain, 131: 2464-78. PDF

Polli, F.E., Barton, J.J.S., Thakkar, K.N., Cain, M.S., Goff, D.C., Rauch, S.L., Manoach, D.S. (2008) Reduced error-related activation in two anterior cingulate circuits is related toimpaired performance in schizophrenia. Brain, 131(4): 971-86. PDF

Barton, J.J.S., Pandita, M.,Thakkar, K.N., Goff, D.C., Manoach, D.S. (2008) The relation between antisaccade errors, fixation stability and prosaccade errors in schizophrenia. Experimental Brain Research, 186(2):273-82. PDF

Commentary
Thakkar, K.N., Matthews, N., Park, S. (2008) A complete theory of psychosis and autism as diametric disorders of the social brain must consider full range of clinical syndromes. Behavioral and Brain Sciences, 31(3): 277-278. PDF

2007 and earlier

Manoach, D.S., Ketwaroo, G.A., Polli, F.E., Thakkar, K.N., Barton, J.J.S., Goff, D.C., Vangel, M., Tuch, D.S. (2007). The association of reduced microstructural integrity of the anterior cingulum bundle is associated with increased saccadic latency in schizophrenia. Neuroimage, 37(2):599-610. PDF

Manoach, D.S., Thakkar, K.N., Cain, M.S., Polli, F.E., Edelman, J., Barton, J.J.S. (2007). Neural activity is modulated by trial history: An fMRI study of the effects of a prior antisaccade. Journal of Neuroscience, 27(7): 1791-1798. PDF

Polli, F.E., Barton, J.J.S., Cain, M.S., Thakkar, K.N. Rauch, S.L., Manoach, D.S (2005). Rostral and dorsal anterior cingulate cortex make dissociable contributions during antisaccade error commission. Proceedings of the National Academy of Sciences, 102(43): 15700-5. PDF

In Press

Lehet, M., Rolfs, M., Bao, J., Fattal, J., Thakkar, K.N. (in press) Pre‐saccadic shifts of attention in individuals diagnosed with schizophrenia. PDF
 

Yao, B., Rolfs, M., Slate, R., Roberts, D., Fattal, J. Achtyes, E.D., Tso, I.F., Diwadkar, V.A., Kashy, D., Bao, J., Thakkar, K.N. (in press) Abnormal oculomotor corollary discharge signaling as a trans-diagnostic mechanism of psychosis. Schizophrenia Bulletin. PDF

Thakkar, K.N., Silverstein, S.M., Fattal, J., Bao, J., Slate, R., Roberts, D., Brascamp, J.W. (in press). Stronger tilt aftereffects in individuals diagnosed with schizophrenia spectrum disorders but not bipolar disorder. Schizophrenia Research. PDF

2024


2023

Roberts, D., Rösler, L., Wijnen, J., Thakkar, K.N. (2023) Associations between N-Acetylaspartate and white matter integrity in individuals with schizophrenia and unaffected relatives. Psychiatry Research: Neuroimaging, 330: 111612. PDF

Thakkar, K.N., McCleery, A., Minor, K.S., Lee, J., Humpston, C.S. Chopik, W.J., Burt, S.A., Pearson, A.L., Ungar, M., Park, S. (2023) Moving from risk to resilience in psychosis research, Nature Reviews Psychology. PDF

Hasan, S.M., Huq, M.S., Chowdury, A.Z., Baajour, S., Kopchick, J., Robison, A.J., Thakkar, K.N., Haddad, L., Amirsadri, A., Thomas, P., Khatib, D., Rajan, U., Stanley, J.A., Diwadkar, V.A. (2023). Learning without contingencies: A loss of synergy between memory and reward circuits in schizophrenia. Schizophrenia Research 258, 21-35. PDF

Merritt, K., Aleman, A., Block, W., [et al, including Thakkar, K.N.] (2023) Variability and Magnitude of Brain Glutamate Levels in Schizophrenia: A Meta And Mega-Analysis. Molecular Psychiatry. PDF

Yao, B., Gu, P., Lasagna, C. A., Peltier, S., Taylor, S. F., Tso, I. F., & Thakkar, K. N. (2023). Structural connectivity of an interoception network in schizophrenia. Psychiatry Research: Neuroimaging, 331: 111636. PDF

2022

Fry BR, Roberts D, Thakkar KN, Johnson AW. (2022). Variables influencing conditioning-evoked hallucinations: overview and future applications. Psychol Med, 1-13. PDF

Culbert, K., Thakkar, K.N., Klump, K. (2022). Risk for midlife psychosis in women: Critical gaps and opportunities in exploring perimenopause and ovarian hormones as mechanisms of risk. Psychological Medicine, 1-9. PDF

Fattal J., Brascamp J.W., Slate R., Lehet, M., Achtyes, E., Thakkar, K.N. (2022) Blunted pupil light reflex is associated with negative symptoms and working memory in individuals with schizophrenia. Schizophrenia Research 248, 254–262. PDF

Migó M., Guillory S.B., McLaughlin C.S., Isenstein E.L., Grosman H.E., Thakkar K.N., Castellanos F.X., Foss-Feig J.H. (2022) Investigating Motor Preparation in Autism Spectrum Disorder With and Without Attention Deficit/Hyperactivity Disorder. Journal of Autism and Developmental Disorders 52, 2379–2387. PDF

Yao, B., Thakkar, K.N. (2022) Interoception abnormalities in schizophrenia: A review of preliminary evidence and an integration with Bayesian accounts of psychosis. Neuroscience and Biobehavioral Reviews 132, 757-773. PDF

2021

Barr, S.M., Roberts, D., Thakkar, K.N. (2021) Psychosis in transgender and gender non-conforming individuals: A review of the literature and a call for more research. Psychiatry Research 306: 114272. PDF

Lehet, M., Tso, I.F., Park, S., Neggers, S.F.W., Thompson, I.A., Kahn, R.S., Thakkar, K.N. (2021) Altered Effective Connectivity within an Oculomotor Control Network in Unaffected Relatives of Individuals with Schizophrenia. Brain Sciences 11(9), 1228. PDF

Yao, B., Rolfs, M., McLaughlin, C., Isenstein, E.L., Guillory, S.B., Grosman, H., Kashy, D.A., Foss-Feig, J.H., Thakkar, K.N. (2021) Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder. Journal of Vision 21(9), 1-20. PDF

Lehet, M., Tso, I.F., Neggers, S.F.W., Thompson, I.A., Yao, B., Kahn, R.S., Thakkar, K.N. (2021) Altered effective connectivity within an oculomotor control network in individuals with schizophrenia. NeuroImage: Clinical 31, 2213-1582. PDF

Dave, A., Lehet, M., Diwadkar, V.A., Thakkar, K.N. (2021) Ocular measures during associative learning predict recall accuracy. International Journal of Psychophysiology 166, 103-115. PDF

Merritt K., McGuire P.K., Egerton A., [et al, including Thakkar, K.N.] (2021) Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data. JAMA Psychiatry 78(6), 667–681. PDF

Chopik, W. J., Oh, J., Nuttall, A. K., Thakkar, K. N., Ingersoll, B. (2021) Age differences in Broader Autism Phenotype traits from young adulthood to older adulthood. Autism Research. PDF

Thakkar, K.N., Mathalon, D.H., Ford, J.M. (2021) Reconciling competing mechanisms posited to underlie auditory verbal hallucinations. Philosophical Transactions of the Royal Society B: Biological Sciences 376, 20190702PDF

Thakkar, K.N., Ghermezi, L., Slate, R., Silverstein, S.M., Achtyes, E.A., Brascamp, J.W., Yao, B. (2021) Stronger tilt aftereffects in persons with schizophrenia. Journal of Abnormal Psychology 130(2), 186-197.  PDF

2020

Yao, B., Neggers, S.F.W., Kahn, R.S., Thakkar, K.N. (2020) Altered thalamocortical structural connectivity in persons with schizophrenia and unaffected siblings. Neuroimage: Clinical, 28: 102370. PDF

Tso, I.F., Lasagna, C.A., Fitzgerald, K.D., Colombi, C. Sripada, C.S., Peltier, S., Johnson, T.D., Thakkar, K.N. (2020) Disrupted eye gaze perception as a biobehavioral marker of social dysfunction: An RDoC investigation. Journal of Psychiatry and Brain Science, 5: e200021. PDF

Robison, A.J., Thakkar, K.N., Diwadkar, V. (2020) Cognition and reward circuits in schizophrenia: synergistic, not separate. Biological Psychiatry, 87, 204-214 PDF 

2019

Thakkar, K.N., Antinori, A., Carter, O., Brascamp, J.W. (2019) Altered short-term synaptic plasticity related to schizotypal traits: evidence from visual adaptation. Schizophrenia Research. PDF

Thakkar, K.N., Rolfs, M. (2019) Disrupted corollary discharge in schizophrenia: evidence from the oculomotor system. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 773-781. PDF

Thakkar, K.N., Silverstein, S.M., Brascamp, J.W. (2019) A review of visual aftereffects in schizophrenia. Neuroscience and Biobehavioral Reviews, 101: 68-77. PDF

Yao, B., Neggers, S.F.W., Rolfs, M., Rösler, L., Thompson, I.A., Hopman, H.J., Ghermezi, L., Kahn, R.S., Thakkar, K.N. (2019) Structural thalamo-frontal hypoconnectivity is related to oculomotor corollary discharge in schizophrenia. Journal of Neuroscience, 39: 2102: 2113. PDF

Nuttall, A.K., Thakkar, K.N., Luo, X., Mueser, K.T., Glynn, S.M., Achtyes, E.D., Kane, J.M. (2019) Longitudinal associations of family burden and patient quality of life in the context of first-episode schizophrenia in the RAISE-ETP study. Psychiatry Research, 276: 60-68. PDF

Verbruggen, F., Aron, A. R., Band, G., [et al, including Thakkar, K.N.] (2019) Capturing the ability to inhibit actions and impulsive behaviors: A consensus guide to the stop-signal task. eLife;8:e46323. PDF

2018

Thakkar, K.N., Brascamp, J.W., Ghermezi, L., Fifer, K., Schall, J.D., Park, S. (2018) Reduced pupil diation during action preparation in schizophrenia. International Journal of Psychophysiology. PDF

Yao, B., Mueller, S., Grove, T., McLaughlin, M., Thakkar, K.N., Ringold, V., McInnis, M., Taylor, S., Deldin, P., Tso, I. (2018) Eye Gaze Perception in Bipolar Disorder: Self-referential Bias but Intact Perceptual Sensitivity. Bipolar Disorders, 20: 60-69. PDF

2017

Thakkar, K.N., Diwadkar, V., Rolfs, M. (2017) Oculomotor prediction: a window into the psychotic mind. Trends in Cognitive Sciences, 21:344-356. PDF

Thakkar, K.N., Rösler, L., Wijnen, J.P., Boer, V.O., Klomp, D.W.J., Cahn, W., Kahn, R.S., Neggers, S.F.W. (2017) 7T proton magnetic resonance spectroscopy of GABA, glutamate, and glutamine in schizophrenia reveals altered metabolite concentrations in patients and unaffected relatives. Biological Psychiatry, 81:525-535.  PDF

2016

Zerr, P., Thakkar, K.N., Uzunbajakau, S., Van der Stigchel, S. (2016) Error compensation in random vector double step saccades with and without global adaptation. Vision Research, 127:141-151. PDF

Thakkar, K.N, van den Heiligenberg, F.M.Z., Kahn, R.S., Neggers, S.F.W. (2016) Cortico-striatal white matter structure predicts latencies of saccade execution and redirection. Human Brain Mapping, 37: 2811-2822.  PDF

Asscheman, S.J., Thakkar, K.N., Neggers, S.F.W. (2016) Changes in effective connectivity of the superior parietal lobe during inhibition and redirection of eye movements. Journal of Experimental Neuroscience, 9(Suppl 1): 27-40.  PDF

2015

Thakkar, K.N., Schall, J.D., Heckers, S., Park, S. (2015) Disrupted saccadic corollary discharge in schizophrenia. Journal of Neuroscience, 35(27): 9935-9945. PDF

Rösler, L., Rolfs, M., van der Stigchel, S., Neggers, S.F.W., Cahn, W., Kahn, R.S, Thakkar, K.N. (2015) Failure to use corollary discharge to remap visual target locations is associated with psychotic symptom severity in schizophrenia. Journal of Neurophysiology, 114: 129-1136. PDF

Thakkar, K.N., Schall, J.D., Logan, G.D., Park, S. (2015) Response inhibition and response monitoring in a saccadic double-step task in schizophrenia. Brain and Cognition, 95: 90-98. PDF

Thakkar, K.N., Schall, J.D., Logan, G.D., Park, S. (2015) Cognitive control of gaze in bipolar disorder and schizophrenia. Psychiatry Research, 225: 254-262. PDF

2014

Thakkar, K.N., van den Heiligenberg, F. Kahn, R.S., Neggers, S.F.W. (2014) Fronto-striatal contributions to reactive control of gaze. Journal of Neuroscience, 34(26): 8918-8929. PDF

Thakkar, K.N., Peterman, J.S., Park, S. (2014) Altered brain activation during action imitation and observation in schizophrenia: a translational approach for studying social dysfunction. American Journal of Psychiatry, 171(5): 539-548. PDF

Thakkar, K.N., Congdon, E., Poldrack, R.A., Sabb, F.W., London, E.D., Cannon, T.D., Bilder, R.M. (2014) Women are more sensitive than men to prior trial events on the stop signal task. British Journal of Psychology, 105(2):254-72. PDF

Matthews, N., Collins, K., Thakkar, K.N., Park, S. (2014) Visuospatial imagery and working memory in schizophrenia. Cognitive Neuropsychiatry, 19(1): 17-35. PDF

2012

Thakkar, K.N., Park, S. (2012) Impaired passive maintenance and spared manipulation of internal representations in patients with schizophrenia. Schizophrenia Bulletin, 38(4): 787-795. PDF

2011

Thakkar, K.N., Nichols, H.S., McIntosh, L.G., Park, S. (2011) Disturbances in body ownership in patients with schizophrenia: evidence from the rubber hand illusion and case study of a spontaneous out-of-body experience. PLoS ONE, 6(10): e27089. PDF

Roffman, J.L., Brohawn, D.G., Friedman, J.S., Dyckman, K.A., Thakkar, K.N., Agam, Y., Vangel, M.G., Goff, D.C., Manoach, D.S. (2011) MTHFR 677C>T effects on anterior cingulate structure and function during response monitoring in schizophrenia: a preliminary study. Brain Imaging and Behavior, 5(1): 65-75. PDF

Thakkar, K.N., Schall, J.D., Boucher, L., Logan, G.D., Park, S. (2011) Response inhibition and response monitoring in a saccadic countermanding task in schizophrenia. Biological Psychiatry, 69: 55-62. PDF

2010

Thakkar, K.N., & Park, S. (2010) Empathy, schizotypy, and spatial transformations. Cognitive Neuropsychiatry, 15: 477-500. PDF

Manoach, D.S., Thakkar, K.N., Stroynowski, E., Ely, A., McKinley, S.K., Djonlagic, I., Vangel,M.G., Goff, D.C., Stickgold, R.S. (2010). Reduced overnight consolidation of procedural learning in chronic medicated schizophrenia is related to specific sleep stages. Journal of Psychiatric Research, 44: 112-120. PDF

Commentary
Park, S. & Thakkar, K.N. (2010) “Splitting of the mind” revisited: recent neuroimaging evidence for functional dysconnection in schizophrenia. American Journal of Psychiatry, 167: 366-368. PDF

2009

Thakkar, K.N., Brugger, P., Park, S. (2009). Exploring empathic space: correlates of perspective transformation ability and biases in spatial attention. PLoS ONE, 4(6): e5864. PDF

2008

Thakkar, K.N., Polli, F.E., Joseph, R.M., Tuch, D.S., Hadjikhani, N., Barton, J.J.S., Manoach, D.S. (2008). Abnormal response monitoring, repetitive behavior, and decreased microstructural integrity of white matter underlying anterior cingulate cortex in autism spectrum disorders. Brain, 131: 2464-78. PDF

Polli, F.E., Barton, J.J.S., Thakkar, K.N., Cain, M.S., Goff, D.C., Rauch, S.L., Manoach, D.S. (2008) Reduced error-related activation in two anterior cingulate circuits is related toimpaired performance in schizophrenia. Brain, 131(4): 971-86. PDF

Barton, J.J.S., Pandita, M.,Thakkar, K.N., Goff, D.C., Manoach, D.S. (2008) The relation between antisaccade errors, fixation stability and prosaccade errors in schizophrenia. Experimental Brain Research, 186(2):273-82. PDF

Commentary
Thakkar, K.N., Matthews, N., Park, S. (2008) A complete theory of psychosis and autism as diametric disorders of the social brain must consider full range of clinical syndromes. Behavioral and Brain Sciences, 31(3): 277-278. PDF

2007 and earlier

Manoach, D.S., Ketwaroo, G.A., Polli, F.E., Thakkar, K.N., Barton, J.J.S., Goff, D.C., Vangel, M., Tuch, D.S. (2007). The association of reduced microstructural integrity of the anterior cingulum bundle is associated with increased saccadic latency in schizophrenia. Neuroimage, 37(2):599-610. PDF

Manoach, D.S., Thakkar, K.N., Cain, M.S., Polli, F.E., Edelman, J., Barton, J.J.S. (2007). Neural activity is modulated by trial history: An fMRI study of the effects of a prior antisaccade. Journal of Neuroscience, 27(7): 1791-1798. PDF

Polli, F.E., Barton, J.J.S., Cain, M.S., Thakkar, K.N. Rauch, S.L., Manoach, D.S (2005). Rostral and dorsal anterior cingulate cortex make dissociable contributions during antisaccade error commission. Proceedings of the National Academy of Sciences, 102(43): 15700-5. PDF

In Press

Lehet, M., Rolfs, M., Bao, J., Fattal, J., Thakkar, K.N. (in press) Pre‐saccadic shifts of attention in individuals diagnosed with schizophrenia. PDF
 

Yao, B., Rolfs, M., Slate, R., Roberts, D., Fattal, J. Achtyes, E.D., Tso, I.F., Diwadkar, V.A., Kashy, D., Bao, J., Thakkar, K.N. (in press) Abnormal oculomotor corollary discharge signaling as a trans-diagnostic mechanism of psychosis. Schizophrenia Bulletin. PDF

Thakkar, K.N., Silverstein, S.M., Fattal, J., Bao, J., Slate, R., Roberts, D., Brascamp, J.W. (in press). Stronger tilt aftereffects in individuals diagnosed with schizophrenia spectrum disorders but not bipolar disorder. Schizophrenia Research. PDF

2024

Lehet, M., Rolfs, M., Bao, J., Fattal, J., Thakkar, K.N. (in press) Pre‐saccadic shifts of attention in individuals diagnosed with schizophrenia. PDF

2023

Roberts, D., Rösler, L., Wijnen, J., Thakkar, K.N. (2023) Associations between N-Acetylaspartate and white matter integrity in individuals with schizophrenia and unaffected relatives. Psychiatry Research: Neuroimaging, 330: 111612. PDF

Thakkar, K.N., McCleery, A., Minor, K.S., Lee, J., Humpston, C.S. Chopik, W.J., Burt, S.A., Pearson, A.L., Ungar, M., Park, S. (2023) Moving from risk to resilience in psychosis research, Nature Reviews Psychology. PDF

Hasan, S.M., Huq, M.S., Chowdury, A.Z., Baajour, S., Kopchick, J., Robison, A.J., Thakkar, K.N., Haddad, L., Amirsadri, A., Thomas, P., Khatib, D., Rajan, U., Stanley, J.A., Diwadkar, V.A. (2023). Learning without contingencies: A loss of synergy between memory and reward circuits in schizophrenia. Schizophrenia Research 258, 21-35. PDF

Merritt, K., Aleman, A., Block, W., [et al, including Thakkar, K.N.] (2023) Variability and Magnitude of Brain Glutamate Levels in Schizophrenia: A Meta And Mega-Analysis. Molecular Psychiatry. PDF

Yao, B., Gu, P., Lasagna, C. A., Peltier, S., Taylor, S. F., Tso, I. F., & Thakkar, K. N. (2023). Structural connectivity of an interoception network in schizophrenia. Psychiatry Research: Neuroimaging, 331: 111636. PDF

2022

Fry BR, Roberts D, Thakkar KN, Johnson AW. (2022). Variables influencing conditioning-evoked hallucinations: overview and future applications. Psychol Med, 1-13. PDF

Culbert, K., Thakkar, K.N., Klump, K. (2022). Risk for midlife psychosis in women: Critical gaps and opportunities in exploring perimenopause and ovarian hormones as mechanisms of risk. Psychological Medicine, 1-9. PDF

Fattal J., Brascamp J.W., Slate R., Lehet, M., Achtyes, E., Thakkar, K.N. (2022) Blunted pupil light reflex is associated with negative symptoms and working memory in individuals with schizophrenia. Schizophrenia Research 248, 254–262. PDF

Migó M., Guillory S.B., McLaughlin C.S., Isenstein E.L., Grosman H.E., Thakkar K.N., Castellanos F.X., Foss-Feig J.H. (2022) Investigating Motor Preparation in Autism Spectrum Disorder With and Without Attention Deficit/Hyperactivity Disorder. Journal of Autism and Developmental Disorders 52, 2379–2387. PDF

Yao, B., Thakkar, K.N. (2022) Interoception abnormalities in schizophrenia: A review of preliminary evidence and an integration with Bayesian accounts of psychosis. Neuroscience and Biobehavioral Reviews 132, 757-773. PDF

2021

Barr, S.M., Roberts, D., Thakkar, K.N. (2021) Psychosis in transgender and gender non-conforming individuals: A review of the literature and a call for more research. Psychiatry Research 306: 114272. PDF

Lehet, M., Tso, I.F., Park, S., Neggers, S.F.W., Thompson, I.A., Kahn, R.S., Thakkar, K.N. (2021) Altered Effective Connectivity within an Oculomotor Control Network in Unaffected Relatives of Individuals with Schizophrenia. Brain Sciences 11(9), 1228. PDF

Yao, B., Rolfs, M., McLaughlin, C., Isenstein, E.L., Guillory, S.B., Grosman, H., Kashy, D.A., Foss-Feig, J.H., Thakkar, K.N. (2021) Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder. Journal of Vision 21(9), 1-20. PDF

Lehet, M., Tso, I.F., Neggers, S.F.W., Thompson, I.A., Yao, B., Kahn, R.S., Thakkar, K.N. (2021) Altered effective connectivity within an oculomotor control network in individuals with schizophrenia. NeuroImage: Clinical 31, 2213-1582. PDF

Dave, A., Lehet, M., Diwadkar, V.A., Thakkar, K.N. (2021) Ocular measures during associative learning predict recall accuracy. International Journal of Psychophysiology 166, 103-115. PDF

Merritt K., McGuire P.K., Egerton A., [et al, including Thakkar, K.N.] (2021) Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data. JAMA Psychiatry 78(6), 667–681. PDF

Chopik, W. J., Oh, J., Nuttall, A. K., Thakkar, K. N., Ingersoll, B. (2021) Age differences in Broader Autism Phenotype traits from young adulthood to older adulthood. Autism Research. PDF

Thakkar, K.N., Mathalon, D.H., Ford, J.M. (2021) Reconciling competing mechanisms posited to underlie auditory verbal hallucinations. Philosophical Transactions of the Royal Society B: Biological Sciences 376, 20190702PDF

Thakkar, K.N., Ghermezi, L., Slate, R., Silverstein, S.M., Achtyes, E.A., Brascamp, J.W., Yao, B. (2021) Stronger tilt aftereffects in persons with schizophrenia. Journal of Abnormal Psychology 130(2), 186-197.  PDF

2020

Yao, B., Neggers, S.F.W., Kahn, R.S., Thakkar, K.N. (2020) Altered thalamocortical structural connectivity in persons with schizophrenia and unaffected siblings. Neuroimage: Clinical, 28: 102370. PDF

Tso, I.F., Lasagna, C.A., Fitzgerald, K.D., Colombi, C. Sripada, C.S., Peltier, S., Johnson, T.D., Thakkar, K.N. (2020) Disrupted eye gaze perception as a biobehavioral marker of social dysfunction: An RDoC investigation. Journal of Psychiatry and Brain Science, 5: e200021. PDF

Robison, A.J., Thakkar, K.N., Diwadkar, V. (2020) Cognition and reward circuits in schizophrenia: synergistic, not separate. Biological Psychiatry, 87, 204-214 PDF 

2019

Thakkar, K.N., Antinori, A., Carter, O., Brascamp, J.W. (2019) Altered short-term synaptic plasticity related to schizotypal traits: evidence from visual adaptation. Schizophrenia Research. PDF

Thakkar, K.N., Rolfs, M. (2019) Disrupted corollary discharge in schizophrenia: evidence from the oculomotor system. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 773-781. PDF

Thakkar, K.N., Silverstein, S.M., Brascamp, J.W. (2019) A review of visual aftereffects in schizophrenia. Neuroscience and Biobehavioral Reviews, 101: 68-77. PDF

Yao, B., Neggers, S.F.W., Rolfs, M., Rösler, L., Thompson, I.A., Hopman, H.J., Ghermezi, L., Kahn, R.S., Thakkar, K.N. (2019) Structural thalamo-frontal hypoconnectivity is related to oculomotor corollary discharge in schizophrenia. Journal of Neuroscience, 39: 2102: 2113. PDF

Nuttall, A.K., Thakkar, K.N., Luo, X., Mueser, K.T., Glynn, S.M., Achtyes, E.D., Kane, J.M. (2019) Longitudinal associations of family burden and patient quality of life in the context of first-episode schizophrenia in the RAISE-ETP study. Psychiatry Research, 276: 60-68. PDF

Verbruggen, F., Aron, A. R., Band, G., [et al, including Thakkar, K.N.] (2019) Capturing the ability to inhibit actions and impulsive behaviors: A consensus guide to the stop-signal task. eLife;8:e46323. PDF

2018

Thakkar, K.N., Brascamp, J.W., Ghermezi, L., Fifer, K., Schall, J.D., Park, S. (2018) Reduced pupil diation during action preparation in schizophrenia. International Journal of Psychophysiology. PDF

Yao, B., Mueller, S., Grove, T., McLaughlin, M., Thakkar, K.N., Ringold, V., McInnis, M., Taylor, S., Deldin, P., Tso, I. (2018) Eye Gaze Perception in Bipolar Disorder: Self-referential Bias but Intact Perceptual Sensitivity. Bipolar Disorders, 20: 60-69. PDF

2017

Thakkar, K.N., Diwadkar, V., Rolfs, M. (2017) Oculomotor prediction: a window into the psychotic mind. Trends in Cognitive Sciences, 21:344-356. PDF

Thakkar, K.N., Rösler, L., Wijnen, J.P., Boer, V.O., Klomp, D.W.J., Cahn, W., Kahn, R.S., Neggers, S.F.W. (2017) 7T proton magnetic resonance spectroscopy of GABA, glutamate, and glutamine in schizophrenia reveals altered metabolite concentrations in patients and unaffected relatives. Biological Psychiatry, 81:525-535.  PDF

2016

Zerr, P., Thakkar, K.N., Uzunbajakau, S., Van der Stigchel, S. (2016) Error compensation in random vector double step saccades with and without global adaptation. Vision Research, 127:141-151. PDF

Thakkar, K.N, van den Heiligenberg, F.M.Z., Kahn, R.S., Neggers, S.F.W. (2016) Cortico-striatal white matter structure predicts latencies of saccade execution and redirection. Human Brain Mapping, 37: 2811-2822.  PDF

Asscheman, S.J., Thakkar, K.N., Neggers, S.F.W. (2016) Changes in effective connectivity of the superior parietal lobe during inhibition and redirection of eye movements. Journal of Experimental Neuroscience, 9(Suppl 1): 27-40.  PDF

2015

Thakkar, K.N., Schall, J.D., Heckers, S., Park, S. (2015) Disrupted saccadic corollary discharge in schizophrenia. Journal of Neuroscience, 35(27): 9935-9945. PDF

Rösler, L., Rolfs, M., van der Stigchel, S., Neggers, S.F.W., Cahn, W., Kahn, R.S, Thakkar, K.N. (2015) Failure to use corollary discharge to remap visual target locations is associated with psychotic symptom severity in schizophrenia. Journal of Neurophysiology, 114: 129-1136. PDF

Thakkar, K.N., Schall, J.D., Logan, G.D., Park, S. (2015) Response inhibition and response monitoring in a saccadic double-step task in schizophrenia. Brain and Cognition, 95: 90-98. PDF

Thakkar, K.N., Schall, J.D., Logan, G.D., Park, S. (2015) Cognitive control of gaze in bipolar disorder and schizophrenia. Psychiatry Research, 225: 254-262. PDF

2014

Thakkar, K.N., van den Heiligenberg, F. Kahn, R.S., Neggers, S.F.W. (2014) Fronto-striatal contributions to reactive control of gaze. Journal of Neuroscience, 34(26): 8918-8929. PDF

Thakkar, K.N., Peterman, J.S., Park, S. (2014) Altered brain activation during action imitation and observation in schizophrenia: a translational approach for studying social dysfunction. American Journal of Psychiatry, 171(5): 539-548. PDF

Thakkar, K.N., Congdon, E., Poldrack, R.A., Sabb, F.W., London, E.D., Cannon, T.D., Bilder, R.M. (2014) Women are more sensitive than men to prior trial events on the stop signal task. British Journal of Psychology, 105(2):254-72. PDF

Matthews, N., Collins, K., Thakkar, K.N., Park, S. (2014) Visuospatial imagery and working memory in schizophrenia. Cognitive Neuropsychiatry, 19(1): 17-35. PDF

2012

Thakkar, K.N., Park, S. (2012) Impaired passive maintenance and spared manipulation of internal representations in patients with schizophrenia. Schizophrenia Bulletin, 38(4): 787-795. PDF

2011

Thakkar, K.N., Nichols, H.S., McIntosh, L.G., Park, S. (2011) Disturbances in body ownership in patients with schizophrenia: evidence from the rubber hand illusion and case study of a spontaneous out-of-body experience. PLoS ONE, 6(10): e27089. PDF

Roffman, J.L., Brohawn, D.G., Friedman, J.S., Dyckman, K.A., Thakkar, K.N., Agam, Y., Vangel, M.G., Goff, D.C., Manoach, D.S. (2011) MTHFR 677C>T effects on anterior cingulate structure and function during response monitoring in schizophrenia: a preliminary study. Brain Imaging and Behavior, 5(1): 65-75. PDF

Thakkar, K.N., Schall, J.D., Boucher, L., Logan, G.D., Park, S. (2011) Response inhibition and response monitoring in a saccadic countermanding task in schizophrenia. Biological Psychiatry, 69: 55-62. PDF

2010

Thakkar, K.N., & Park, S. (2010) Empathy, schizotypy, and spatial transformations. Cognitive Neuropsychiatry, 15: 477-500. PDF

Manoach, D.S., Thakkar, K.N., Stroynowski, E., Ely, A., McKinley, S.K., Djonlagic, I., Vangel,M.G., Goff, D.C., Stickgold, R.S. (2010). Reduced overnight consolidation of procedural learning in chronic medicated schizophrenia is related to specific sleep stages. Journal of Psychiatric Research, 44: 112-120. PDF

Commentary
Park, S. & Thakkar, K.N. (2010) “Splitting of the mind” revisited: recent neuroimaging evidence for functional dysconnection in schizophrenia. American Journal of Psychiatry, 167: 366-368. PDF

2009

Thakkar, K.N., Brugger, P., Park, S. (2009). Exploring empathic space: correlates of perspective transformation ability and biases in spatial attention. PLoS ONE, 4(6): e5864. PDF

2008

Thakkar, K.N., Polli, F.E., Joseph, R.M., Tuch, D.S., Hadjikhani, N., Barton, J.J.S., Manoach, D.S. (2008). Abnormal response monitoring, repetitive behavior, and decreased microstructural integrity of white matter underlying anterior cingulate cortex in autism spectrum disorders. Brain, 131: 2464-78. PDF

Polli, F.E., Barton, J.J.S., Thakkar, K.N., Cain, M.S., Goff, D.C., Rauch, S.L., Manoach, D.S. (2008) Reduced error-related activation in two anterior cingulate circuits is related toimpaired performance in schizophrenia. Brain, 131(4): 971-86. PDF

Barton, J.J.S., Pandita, M.,Thakkar, K.N., Goff, D.C., Manoach, D.S. (2008) The relation between antisaccade errors, fixation stability and prosaccade errors in schizophrenia. Experimental Brain Research, 186(2):273-82. PDF

Commentary
Thakkar, K.N., Matthews, N., Park, S. (2008) A complete theory of psychosis and autism as diametric disorders of the social brain must consider full range of clinical syndromes. Behavioral and Brain Sciences, 31(3): 277-278. PDF

2007 and earlier

Manoach, D.S., Ketwaroo, G.A., Polli, F.E., Thakkar, K.N., Barton, J.J.S., Goff, D.C., Vangel, M., Tuch, D.S. (2007). The association of reduced microstructural integrity of the anterior cingulum bundle is associated with increased saccadic latency in schizophrenia. Neuroimage, 37(2):599-610. PDF

Manoach, D.S., Thakkar, K.N., Cain, M.S., Polli, F.E., Edelman, J., Barton, J.J.S. (2007). Neural activity is modulated by trial history: An fMRI study of the effects of a prior antisaccade. Journal of Neuroscience, 27(7): 1791-1798. PDF

Polli, F.E., Barton, J.J.S., Cain, M.S., Thakkar, K.N. Rauch, S.L., Manoach, D.S (2005). Rostral and dorsal anterior cingulate cortex make dissociable contributions during antisaccade error commission. Proceedings of the National Academy of Sciences, 102(43): 15700-5. PDF

In Press


Yao, B., Rolfs, M., Slate, R., Roberts, D., Fattal, J. Achtyes, E.D., Tso, I.F., Diwadkar, V.A., Kashy, D., Bao, J., Thakkar, K.N. (in press) Abnormal oculomotor corollary discharge signaling as a trans-diagnostic mechanism of psychosis. Schizophrenia Bulletin. PDF

Thakkar, K.N., Silverstein, S.M., Fattal, J., Bao, J., Slate, R., Roberts, D., Brascamp, J.W. (in press). Stronger tilt aftereffects in individuals diagnosed with schizophrenia spectrum disorders but not bipolar disorder. Schizophrenia Research. PDF

2023

Roberts, D., Rösler, L., Wijnen, J., Thakkar, K.N. (2023) Associations between N-Acetylaspartate and white matter integrity in individuals with schizophrenia and unaffected relatives. Psychiatry Research: Neuroimaging, 330: 111612. PDF

Thakkar, K.N., McCleery, A., Minor, K.S., Lee, J., Humpston, C.S. Chopik, W.J., Burt, S.A., Pearson, A.L., Ungar, M., Park, S. (2023) Moving from risk to resilience in psychosis research, Nature Reviews Psychology. PDF

Hasan, S.M., Huq, M.S., Chowdury, A.Z., Baajour, S., Kopchick, J., Robison, A.J., Thakkar, K.N., Haddad, L., Amirsadri, A., Thomas, P., Khatib, D., Rajan, U., Stanley, J.A., Diwadkar, V.A. (2023). Learning without contingencies: A loss of synergy between memory and reward circuits in schizophrenia. Schizophrenia Research 258, 21-35. PDF

Merritt, K., Aleman, A., Block, W., [et al, including Thakkar, K.N.] (2023) Variability and Magnitude of Brain Glutamate Levels in Schizophrenia: A Meta And Mega-Analysis. Molecular Psychiatry. PDF

Yao, B., Gu, P., Lasagna, C. A., Peltier, S., Taylor, S. F., Tso, I. F., & Thakkar, K. N. (2023). Structural connectivity of an interoception network in schizophrenia. Psychiatry Research: Neuroimaging, 331: 111636. PDF

2022

Fry BR, Roberts D, Thakkar KN, Johnson AW. (2022). Variables influencing conditioning-evoked hallucinations: overview and future applications. Psychol Med, 1-13. PDF

Culbert, K., Thakkar, K.N., Klump, K. (2022). Risk for midlife psychosis in women: Critical gaps and opportunities in exploring perimenopause and ovarian hormones as mechanisms of risk. Psychological Medicine, 1-9. PDF

Fattal J., Brascamp J.W., Slate R., Lehet, M., Achtyes, E., Thakkar, K.N. (2022) Blunted pupil light reflex is associated with negative symptoms and working memory in individuals with schizophrenia. Schizophrenia Research 248, 254–262. PDF

Migó M., Guillory S.B., McLaughlin C.S., Isenstein E.L., Grosman H.E., Thakkar K.N., Castellanos F.X., Foss-Feig J.H. (2022) Investigating Motor Preparation in Autism Spectrum Disorder With and Without Attention Deficit/Hyperactivity Disorder. Journal of Autism and Developmental Disorders 52, 2379–2387. PDF

Yao, B., Thakkar, K.N. (2022) Interoception abnormalities in schizophrenia: A review of preliminary evidence and an integration with Bayesian accounts of psychosis. Neuroscience and Biobehavioral Reviews 132, 757-773. PDF

2021

Barr, S.M., Roberts, D., Thakkar, K.N. (2021) Psychosis in transgender and gender non-conforming individuals: A review of the literature and a call for more research. Psychiatry Research 306: 114272. PDF

Lehet, M., Tso, I.F., Park, S., Neggers, S.F.W., Thompson, I.A., Kahn, R.S., Thakkar, K.N. (2021) Altered Effective Connectivity within an Oculomotor Control Network in Unaffected Relatives of Individuals with Schizophrenia. Brain Sciences 11(9), 1228. PDF

Yao, B., Rolfs, M., McLaughlin, C., Isenstein, E.L., Guillory, S.B., Grosman, H., Kashy, D.A., Foss-Feig, J.H., Thakkar, K.N. (2021) Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder. Journal of Vision 21(9), 1-20. PDF

Lehet, M., Tso, I.F., Neggers, S.F.W., Thompson, I.A., Yao, B., Kahn, R.S., Thakkar, K.N. (2021) Altered effective connectivity within an oculomotor control network in individuals with schizophrenia. NeuroImage: Clinical 31, 2213-1582. PDF

Dave, A., Lehet, M., Diwadkar, V.A., Thakkar, K.N. (2021) Ocular measures during associative learning predict recall accuracy. International Journal of Psychophysiology 166, 103-115. PDF

Merritt K., McGuire P.K., Egerton A., [et al, including Thakkar, K.N.] (2021) Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data. JAMA Psychiatry 78(6), 667–681. PDF

Chopik, W. J., Oh, J., Nuttall, A. K., Thakkar, K. N., Ingersoll, B. (2021) Age differences in Broader Autism Phenotype traits from young adulthood to older adulthood. Autism Research. PDF

Thakkar, K.N., Mathalon, D.H., Ford, J.M. (2021) Reconciling competing mechanisms posited to underlie auditory verbal hallucinations. Philosophical Transactions of the Royal Society B: Biological Sciences 376, 20190702PDF

Thakkar, K.N., Ghermezi, L., Slate, R., Silverstein, S.M., Achtyes, E.A., Brascamp, J.W., Yao, B. (2021) Stronger tilt aftereffects in persons with schizophrenia. Journal of Abnormal Psychology 130(2), 186-197.  PDF

2020

Yao, B., Neggers, S.F.W., Kahn, R.S., Thakkar, K.N. (2020) Altered thalamocortical structural connectivity in persons with schizophrenia and unaffected siblings. Neuroimage: Clinical, 28: 102370. PDF

Tso, I.F., Lasagna, C.A., Fitzgerald, K.D., Colombi, C. Sripada, C.S., Peltier, S., Johnson, T.D., Thakkar, K.N. (2020) Disrupted eye gaze perception as a biobehavioral marker of social dysfunction: An RDoC investigation. Journal of Psychiatry and Brain Science, 5: e200021. PDF

Robison, A.J., Thakkar, K.N., Diwadkar, V. (2020) Cognition and reward circuits in schizophrenia: synergistic, not separate. Biological Psychiatry, 87, 204-214 PDF 

2019

Thakkar, K.N., Antinori, A., Carter, O., Brascamp, J.W. (2019) Altered short-term synaptic plasticity related to schizotypal traits: evidence from visual adaptation. Schizophrenia Research. PDF

Thakkar, K.N., Rolfs, M. (2019) Disrupted corollary discharge in schizophrenia: evidence from the oculomotor system. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 773-781. PDF

Thakkar, K.N., Silverstein, S.M., Brascamp, J.W. (2019) A review of visual aftereffects in schizophrenia. Neuroscience and Biobehavioral Reviews, 101: 68-77. PDF

Yao, B., Neggers, S.F.W., Rolfs, M., Rösler, L., Thompson, I.A., Hopman, H.J., Ghermezi, L., Kahn, R.S., Thakkar, K.N. (2019) Structural thalamo-frontal hypoconnectivity is related to oculomotor corollary discharge in schizophrenia. Journal of Neuroscience, 39: 2102: 2113. PDF

Nuttall, A.K., Thakkar, K.N., Luo, X., Mueser, K.T., Glynn, S.M., Achtyes, E.D., Kane, J.M. (2019) Longitudinal associations of family burden and patient quality of life in the context of first-episode schizophrenia in the RAISE-ETP study. Psychiatry Research, 276: 60-68. PDF

Verbruggen, F., Aron, A. R., Band, G., [et al, including Thakkar, K.N.] (2019) Capturing the ability to inhibit actions and impulsive behaviors: A consensus guide to the stop-signal task. eLife;8:e46323. PDF

2018

Thakkar, K.N., Brascamp, J.W., Ghermezi, L., Fifer, K., Schall, J.D., Park, S. (2018) Reduced pupil diation during action preparation in schizophrenia. International Journal of Psychophysiology. PDF

Yao, B., Mueller, S., Grove, T., McLaughlin, M., Thakkar, K.N., Ringold, V., McInnis, M., Taylor, S., Deldin, P., Tso, I. (2018) Eye Gaze Perception in Bipolar Disorder: Self-referential Bias but Intact Perceptual Sensitivity. Bipolar Disorders, 20: 60-69. PDF

2017

Thakkar, K.N., Diwadkar, V., Rolfs, M. (2017) Oculomotor prediction: a window into the psychotic mind. Trends in Cognitive Sciences, 21:344-356. PDF

Thakkar, K.N., Rösler, L., Wijnen, J.P., Boer, V.O., Klomp, D.W.J., Cahn, W., Kahn, R.S., Neggers, S.F.W. (2017) 7T proton magnetic resonance spectroscopy of GABA, glutamate, and glutamine in schizophrenia reveals altered metabolite concentrations in patients and unaffected relatives. Biological Psychiatry, 81:525-535.  PDF

2016

Zerr, P., Thakkar, K.N., Uzunbajakau, S., Van der Stigchel, S. (2016) Error compensation in random vector double step saccades with and without global adaptation. Vision Research, 127:141-151. PDF

Thakkar, K.N, van den Heiligenberg, F.M.Z., Kahn, R.S., Neggers, S.F.W. (2016) Cortico-striatal white matter structure predicts latencies of saccade execution and redirection. Human Brain Mapping, 37: 2811-2822.  PDF

Asscheman, S.J., Thakkar, K.N., Neggers, S.F.W. (2016) Changes in effective connectivity of the superior parietal lobe during inhibition and redirection of eye movements. Journal of Experimental Neuroscience, 9(Suppl 1): 27-40.  PDF

2015

Thakkar, K.N., Schall, J.D., Heckers, S., Park, S. (2015) Disrupted saccadic corollary discharge in schizophrenia. Journal of Neuroscience, 35(27): 9935-9945. PDF

Rösler, L., Rolfs, M., van der Stigchel, S., Neggers, S.F.W., Cahn, W., Kahn, R.S, Thakkar, K.N. (2015) Failure to use corollary discharge to remap visual target locations is associated with psychotic symptom severity in schizophrenia. Journal of Neurophysiology, 114: 129-1136. PDF

Thakkar, K.N., Schall, J.D., Logan, G.D., Park, S. (2015) Response inhibition and response monitoring in a saccadic double-step task in schizophrenia. Brain and Cognition, 95: 90-98. PDF

Thakkar, K.N., Schall, J.D., Logan, G.D., Park, S. (2015) Cognitive control of gaze in bipolar disorder and schizophrenia. Psychiatry Research, 225: 254-262. PDF

2014

Thakkar, K.N., van den Heiligenberg, F. Kahn, R.S., Neggers, S.F.W. (2014) Fronto-striatal contributions to reactive control of gaze. Journal of Neuroscience, 34(26): 8918-8929. PDF

Thakkar, K.N., Peterman, J.S., Park, S. (2014) Altered brain activation during action imitation and observation in schizophrenia: a translational approach for studying social dysfunction. American Journal of Psychiatry, 171(5): 539-548. PDF

Thakkar, K.N., Congdon, E., Poldrack, R.A., Sabb, F.W., London, E.D., Cannon, T.D., Bilder, R.M. (2014) Women are more sensitive than men to prior trial events on the stop signal task. British Journal of Psychology, 105(2):254-72. PDF

Matthews, N., Collins, K., Thakkar, K.N., Park, S. (2014) Visuospatial imagery and working memory in schizophrenia. Cognitive Neuropsychiatry, 19(1): 17-35. PDF

2012

Thakkar, K.N., Park, S. (2012) Impaired passive maintenance and spared manipulation of internal representations in patients with schizophrenia. Schizophrenia Bulletin, 38(4): 787-795. PDF

2011

Thakkar, K.N., Nichols, H.S., McIntosh, L.G., Park, S. (2011) Disturbances in body ownership in patients with schizophrenia: evidence from the rubber hand illusion and case study of a spontaneous out-of-body experience. PLoS ONE, 6(10): e27089. PDF

Roffman, J.L., Brohawn, D.G., Friedman, J.S., Dyckman, K.A., Thakkar, K.N., Agam, Y., Vangel, M.G., Goff, D.C., Manoach, D.S. (2011) MTHFR 677C>T effects on anterior cingulate structure and function during response monitoring in schizophrenia: a preliminary study. Brain Imaging and Behavior, 5(1): 65-75. PDF

Thakkar, K.N., Schall, J.D., Boucher, L., Logan, G.D., Park, S. (2011) Response inhibition and response monitoring in a saccadic countermanding task in schizophrenia. Biological Psychiatry, 69: 55-62. PDF

2010

Thakkar, K.N., & Park, S. (2010) Empathy, schizotypy, and spatial transformations. Cognitive Neuropsychiatry, 15: 477-500. PDF

Manoach, D.S., Thakkar, K.N., Stroynowski, E., Ely, A., McKinley, S.K., Djonlagic, I., Vangel,M.G., Goff, D.C., Stickgold, R.S. (2010). Reduced overnight consolidation of procedural learning in chronic medicated schizophrenia is related to specific sleep stages. Journal of Psychiatric Research, 44: 112-120. PDF

Commentary
Park, S. & Thakkar, K.N. (2010) “Splitting of the mind” revisited: recent neuroimaging evidence for functional dysconnection in schizophrenia. American Journal of Psychiatry, 167: 366-368. PDF

2009

Thakkar, K.N., Brugger, P., Park, S. (2009). Exploring empathic space: correlates of perspective transformation ability and biases in spatial attention. PLoS ONE, 4(6): e5864. PDF

2008

Thakkar, K.N., Polli, F.E., Joseph, R.M., Tuch, D.S., Hadjikhani, N., Barton, J.J.S., Manoach, D.S. (2008). Abnormal response monitoring, repetitive behavior, and decreased microstructural integrity of white matter underlying anterior cingulate cortex in autism spectrum disorders. Brain, 131: 2464-78. PDF

Polli, F.E., Barton, J.J.S., Thakkar, K.N., Cain, M.S., Goff, D.C., Rauch, S.L., Manoach, D.S. (2008) Reduced error-related activation in two anterior cingulate circuits is related toimpaired performance in schizophrenia. Brain, 131(4): 971-86. PDF

Barton, J.J.S., Pandita, M.,Thakkar, K.N., Goff, D.C., Manoach, D.S. (2008) The relation between antisaccade errors, fixation stability and prosaccade errors in schizophrenia. Experimental Brain Research, 186(2):273-82. PDF

Commentary
Thakkar, K.N., Matthews, N., Park, S. (2008) A complete theory of psychosis and autism as diametric disorders of the social brain must consider full range of clinical syndromes. Behavioral and Brain Sciences, 31(3): 277-278. PDF

2007 and earlier

Manoach, D.S., Ketwaroo, G.A., Polli, F.E., Thakkar, K.N., Barton, J.J.S., Goff, D.C., Vangel, M., Tuch, D.S. (2007). The association of reduced microstructural integrity of the anterior cingulum bundle is associated with increased saccadic latency in schizophrenia. Neuroimage, 37(2):599-610. PDF

Manoach, D.S., Thakkar, K.N., Cain, M.S., Polli, F.E., Edelman, J., Barton, J.J.S. (2007). Neural activity is modulated by trial history: An fMRI study of the effects of a prior antisaccade. Journal of Neuroscience, 27(7): 1791-1798. PDF

Polli, F.E., Barton, J.J.S., Cain, M.S., Thakkar, K.N. Rauch, S.L., Manoach, D.S (2005). Rostral and dorsal anterior cingulate cortex make dissociable contributions during antisaccade error commission. Proceedings of the National Academy of Sciences, 102(43): 15700-5. PDF